Multiplexing Proteomic Biomarkers
With our partners, we are devloping proteomics panels for disease detection, monitoring and stratification through our patented system for high sensitivity, high dynamic range, efficient multiplexing. The system enables easy panel adaption at manufacture and for end-user customization.
Biomarker Measurement in femtogram/ml and 5 log unit dynamic range
Biomarker Measurement in femtogram/ml and 5 log unit dynamic range
Proteomics for disease detection, stratification and therapeutic MoA
We are in collaboration with partners across multiple therapeutic areas in disease detection, stratification and therapeutic mechanism of action.
The proteomic system efficiency in operation generates robust readout within high sensitivity and high dynamic range multiplexing in up to 150 markers.
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One of our core specialities is providing design of customized marker panels from our depth of transational and therapeutic development experience.
We optimize biomarker strategies to distil biomarker signatures for stratification and mechanism of action.
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Integration of Aeirtec's proprietary biochemistry and patented curve analysis equations enable Aeirtec to extend sample marker quantification into the low femtogram/ml region with precision and with a 5 log dynamic range.
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Our biostatisticians possess expertise in the often ignored, but critcial, correct data preparation prior to statistical application for distillation of group biomarker signatures.
We conduct univariate and multvariate statistics to assist in bioinformatics based machine learning conducted through our partners.
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Across our team, we have decades of clinical research experience in translational research and clinical trial conduct. We are founded by pharmacologists and clinical pharmacologists providing Aeirtec with capacity for data interpretation in a cellular to clinical context across a wide range of therapeutic areas.
QC/QA: Our marker panels are fully validated prior to sample analysis. Each assay panel incorporates realtime calibration curves for critical parallel measurements of lower and upper limits of quantification (LLOQ and ULOQ) and mass/volume (low fg/ml to ng/ml) at the time of assay for accuracy. Each assay plate can be repeatedly analyzed indefinitely for QC checks.
Our research is conducted under the principles of GLP, GMP and ISO17025:2017 compliance in conjunction with internal and external independent Quality Assurance.
Our Development Expertise
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Patented Technology
High sensitivity high dynamic range proteomic multiplexing activity at Aeirtec
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About Us
Examples of our work and expertise
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Customization of Markers
Therapeutic area-specific marker panel customization
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Multivariate Biostatistics
Better data interpretation with multivariate biostatistics and machine learning / AI