Many initiating mediators of cascade responses , such as immune/inflammatory response initiating markers (eg. TNF, IFN, IL-1, IL-2, IL-4, IL-6) are primary candidates for inclusion in study assay panels, because of their doinance in the action hierarchy.

However, these initiating markers typically exist at low abundance levels and below the level of quantification of many standard immunoassays.

Aeirtec avoids the loss of subject data, typical of standard assay sensitivity, by applying their integration of patented and proprietary biochemical assay techniques.

Increasing assay sensitivity increases the capacity for capturing quantification of low abundance critical markers by an order of magnitude - essential for maintaining biomarker-denedent study power.