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Custom Marker Panels
As an option in the Integrated Service we provide help with design, or entirely design, multiplex panels for a wide range of clincial and basic research studies. We then progress to construction and validation of the selected assay panel.
Using commerially available and validated antibodies we also generate assays for novel proteins or peptides for incorporation into multiplex panel construction and validation. Therefore, markers from a range of different marker classes can be brought together within the same multiplex panel.
Ultra High Sensitivity Immunoassay
Aeirtec has focused assay development on generation of the highest sensitivity customised multiplex activity available. This goal was set to avoid the problem of ‘below level of detection’ data and thereby retain study power through retention of data on all samples. Aeirtec has developed and incorporated proporietary unique assay technology to realise this goal.
Even with the incorporation of such high sensitivity, multiplexing within Aeirtec remains the most cost efficient immunoassay route for even low numbers of markers within samples and therefore also remains a cheaper option than single ELISA kit assay.
Data Interpretation Through Bioinformatics
We can apply bioinformatics to multiplexed data of even relatively small marker numbers. Following data organisation into differing data indices, an example, multivariate analysis-guided hierarchical cluster analysis is conducted to monitor marker group activity as integrated constellations.
This activity reveals the greater power of marker groups to act in consort to provide prediction and characterisation of biological states and events.
Aeirtec provides modular options within a 'one stop shop' integrated service of (1) custom marker panel design, (2) ultrasensitive multiplex marker measurement and (3) data interpretation through bioinformatics. This activity is provided under GLP and ISO 17025 compliance with independent QA.